Student research published in international science journal

Shreyam Tripathi, a member of the Arkansas School for Mathematics, Sciences and the Arts Class of 2023, recently had a paper on his research published in RSC Chemical Biology, a scholarly journal published by the Royal Society of Chemistry.

Tripathi’s paper focused on the replication of the G-quadraplex (G4), a secondary structure that genomic DNA adopts and plays a vital part in cellular regulation. He focused on the importance of Rev1 in G4 DNA replication as well as the importance of the placement of the G4 motif within a certain gene.

The Royal Society of Chemistry is an association that works to advance the chemical sciences through a professional association, scientific journal, conferences and other means.

Tripathi initially conducted his research for a capstone project at ASMSA. He was recognized for his work at both the West Central Regional Science Fair at ASMSA in February, where he won first place overall, as well as receiving a Fourth Grand Award in the Translational Medical Science category at the 2023 Regeneron International Science and Engineering Fair in mid-May.

He found out that his paper had officially been published in the journal judging day at ISEF. He knew it had been accepted for publication earlier in the month, but actually seeing it published was a relief.

“Seeing my name on the paper and seeing my work published felt so surreal,” Tripathi said. “Earning a publication in a scholarly journal is a really big deal, especially since I’m a high-schooler. Having my work recognized in this fashion means that all my hard work is recognized, not only by my mentors at ASMSA and my lab colleagues at (the University of Arkansas for Medical Sciences), but also by the scientific community worldwide. The countless hours that I worked in the lab during winter break, spring break and all of summer were truly worth it.”

Tripathi worked on the manuscript of the journal submission with Dr. Robert Eoff, a faculty member in the Department of Biochemistry and Molecular Biology at UAMS’ College of Medicine. Eoff was Tripathi’s lab mentor.

He originally submitted the paper to a different journal, who made numerous suggestions and asked for edits before considering it for publication. On Eoff’s advice, he made some of the edits and submitted the manuscript to the Royal Society of Chemistry. They suggested just a few revisions, which Tripathi made and resubmitted it for publication. This time it was accepted.

When he found out that the paper had officially been published, he shared the news on a family group chat. That included a little ribbing of his older brother, Sanidhya, a Class of 2018 alumnus.

“I was joking around with my brother about how I got published in a better journal than he did when he was in high school,” he said.

To read the article, visit https://asmsa.me/tripathijournal23.

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